SU couldn't overcome at a 34-7 haft time deficit, falling to the Wildcats, 48-27.
Senior quarterback Drew Allen threw four interceptions and Syracuse (0-2) fell to Northwestern (2-0) 48-27.
The Orange defense struggled early on and gave up a touchdown on the first drive of the game when Wildcat quarterback Kain Colter connected with junior running back Treyvon Green for a 8-yard passing play.