Syracuse is now on a four-game losing streak after another away loss.
When Syracuse (4-7, 2-5 ACC) entered Papa John's Cardinal Stadium, the Orange had a slim chance to win. Rain fell almost the entire game, including a forty-three minute delay in the second quarter, but it was no contest as the Louisville Cardinals ended the game with 727 yards for the night, and Syracuse only 335. As a result, Syracuse failed to win a road game this season, and the team has failed to qualify for bowl contention for a fourth year in a row.